Apocynin preserves glutamatergic neurons in the basolateral amygdala in mice with neonatal sevoflurane exposure

Apocynin preserves glutamatergic neurons in the basolateral amygdala in mice with neonatal sevoflurane exposure

BackgroundNeonatal exposure to anesthetics induces neuronal apoptosis and long-term cognitive dysfunction in rodents. We showed that the nicotinamide adenine dinucleotide phosphate-oxidase inhibitor apocynin not only reduces neurotoxicity by decreasing superoxide levels and preventing mitochondrial...

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Bibliographic Details
Main Authors: Zhongliang Sun, Maiko Satomoto, Yushi U Adachi, Koshi Makita
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2017-06-01
Series:Korean Journal of Anesthesiology
Subjects:
anesthesia
brain
neurotoxicity
pediatrics
sevoflurane
Online Access:http://ekja.org/upload/pdf/kjae-70-335.pdf

Internet

http://ekja.org/upload/pdf/kjae-70-335.pdf

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