Robustness and backbone motif of a cancer network regulated by miR-17-92 cluster during the G1/S transition.

Robustness and backbone motif of a cancer network regulated by miR-17-92 cluster during the G1/S transition.

Based on interactions among transcription factors, oncogenes, tumor suppressors and microRNAs, a Boolean model of cancer network regulated by miR-17-92 cluster is constructed, and the network is associated with the control of G1/S transition in the mammalian cell cycle. The robustness properties of...

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Bibliographic Details
Main Authors: Lijian Yang, Yan Meng, Chun Bao, Wangheng Liu, Chengzhang Ma, Anbang Li, Zhan Xuan, Ge Shan, Ya Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585929?pdf=render

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http://europepmc.org/articles/PMC3585929?pdf=render

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