Expression of the Inhibitory Receptor TIGIT Is Up-Regulated Specifically on NK Cells With CD226 Activating Receptor From HIV-Infected Individuals

Expression of the Inhibitory Receptor TIGIT Is Up-Regulated Specifically on NK Cells With CD226 Activating Receptor From HIV-Infected Individuals

Natural killer (NK) cells are important for maintenance of innate immune system stability and serve as a first line of defense against tumors and virus infections; they can act either directly or indirectly and are regulated via co-operation between inhibitory and stimulatory surface receptors. The...

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Bibliographic Details
Main Authors: Xiaowan Yin, Tingting Liu, Zhuo Wang, Meichen Ma, Jie Lei, Zining Zhang, Shuai Fu, Yajing Fu, Qinghai Hu, Haibo Ding, Xiaoxu Han, Junjie Xu, Hong Shang, Yongjun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
TIGIT
CD226
CD155
NK cell
HIV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02341/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02341/full

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