Association between metformin use and disease progression in obese people with knee osteoarthritis: data from the Osteoarthritis Initiative—a prospective cohort study

Association between metformin use and disease progression in obese people with knee osteoarthritis: data from the Osteoarthritis Initiative—a prospective cohort study

Abstract Objective To examine whether metformin use was associated with knee cartilage volume loss over 4 years and risk of total knee replacement over 6 years in obese individuals with knee osteoarthritis. Methods This study analysed the Osteoarthritis Initiative participants with radiographic knee...

Full description

Bibliographic Details
Main Authors: Yuanyuan Wang, Sultana Monira Hussain, Anita E. Wluka, Yuan Z. Lim, François Abram, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Flavia M. Cicuttini
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Arthritis Research & Therapy
Subjects:
Metformin
Osteoarthritis
Cartilage
Total knee replacement
Online Access:http://link.springer.com/article/10.1186/s13075-019-1915-x

Internet

http://link.springer.com/article/10.1186/s13075-019-1915-x

Similar Items