Generation of Monoclonal Antibodies against Ag85A Antigen of Mycobacterium tuberculosis and Application in a Competitive ELISA for Serodiagnosis of Bovine Tuberculosis

Generation of Monoclonal Antibodies against Ag85A Antigen of Mycobacterium tuberculosis and Application in a Competitive ELISA for Serodiagnosis of Bovine Tuberculosis

The Ag85 complex functions as the main secretory protein of Mycobacterium tuberculosis (M. tuberculosis) and BCG. This complex is composed of the proteins, Ag85A, Ag85B, and Ag85C, with Ag85A thought to play the largest role within the complex. However, the lack of commercially available monoclonal...

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Bibliographic Details
Main Authors: Zhengzhong Xu, Ting Hu, Aihong Xia, Xin Li, Ze Liu, Jingjing Min, Jingjing He, Chuang Meng, Yuelan Yin, Xiang Chen, Xinan Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Veterinary Science
Subjects:
Mycobacterium tuberculosis
Ag85A
Monoclonal antibody
cross-react
competitive ELISA
bovine tuberculosis
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2017.00107/full

Internet

http://journal.frontiersin.org/article/10.3389/fvets.2017.00107/full

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