Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice

Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice

Fatty liver involves ectopic lipid accumulation and dysregulated hepatic oxidative metabolism, which can progress to a state of elevated inflammation and fibrosis referred to as nonalcoholic steatohepatitis (NASH). The factors that control progression from simple steatosis to NASH are not fully know...

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Bibliographic Details
Main Authors: Clinton M. Hasenour, Arion J. Kennedy, Tomasz Bednarski, Irina A. Trenary, Brandon J. Eudy, Robin P. da Silva, Kelli L. Boyd, Jamey D. Young
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Lipid Research
Subjects:
nonalcoholic steatohepatitis
nonalcoholic fatty liver disease
phospholipids
triglycerides
ceramides
gluconeogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752043620X

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http://www.sciencedirect.com/science/article/pii/S002222752043620X

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