Mitochondrial Dysfunction in Pancreatic Alpha and Beta Cells Associated with Type 2 Diabetes Mellitus

Mitochondrial Dysfunction in Pancreatic Alpha and Beta Cells Associated with Type 2 Diabetes Mellitus

Type 2 diabetes mellitus is a complex multifactorial disease of epidemic proportions. It involves genetic and lifestyle factors that lead to dysregulations in hormone secretion and metabolic homeostasis. Accumulating evidence indicates that altered mitochondrial structure, function, and particularly...

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Bibliographic Details
Main Authors: Vladimir Grubelnik, Jan Zmazek, Rene Markovič, Marko Gosak, Marko Marhl
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Life
Subjects:
pancreatic endocrine cells
mathematical model
mitochondrial dysfunction
cellular bioenergetics
diabetes
glucagon
Online Access:https://www.mdpi.com/2075-1729/10/12/348

Internet

https://www.mdpi.com/2075-1729/10/12/348

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