Perineuronal nets increase inhibitory GABAergic currents during the critical period in rats

Perineuronal nets increase inhibitory GABAergic currents during the critical period in rats

AIM: To investigate inhibitory γ-aminobutyric acid (GABA) ergic postsynaptic currents (IPSCs) and postsynaptic currents (PSCs) in layer IV of the rat visual cortex during the critical period and when plasticity was extended through dissolution of the perineuronal nets (PNNs).METHODS:We employed 24 n...

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Bibliographic Details
Main Authors: Zheng-Qin Yin, Jun-Ping Yao, Tao Yu, Ming-Ming Liu, Hai-Wei Xu, Peng-Fen Gao, Hui Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2013-04-01
Series:International Journal of Ophthalmology
Subjects:
gamma-aminobutyric acid receptor
plasticity
visual cortex
development
postsynaptic
currents
chondroitinase ABC
chondroitin sulfate proteoglycans
whole-cell patch recording
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633745/

Internet

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633745/

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