Hepcidin Downregulation Correlates With Disease Aggressiveness And Immune Infiltration in Liver Cancers

BackgroundHepcidin is a polypeptide hormone mainly produced by hepatocytes to modulate systemic iron balance. A drastic downregulation of the hepcidin gene was found in liver cancers. However, there is a paucity of information about the clinical significance of hepcidin gene downregulation in liver...

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Bibliographic Details
Main Authors: Jinhu Wang, Wang Liu, Jean C. Li, Mingyi Li, Benyi Li, Runzhi Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.714756/full