SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans.

Centrioles are microtubule-based organelles important for the formation of cilia, flagella and centrosomes. Despite progress in understanding the underlying assembly mechanisms, how centriole integrity is ensured is incompletely understood, including in sperm cells, where such integrity is particula...

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Bibliographic Details
Main Authors: Lukas von Tobel, Tamara Mikeladze-Dvali, Marie Delattre, Fernando R Balestra, Simon Blanchoud, Susanne Finger, Graham Knott, Thomas Müller-Reichert, Pierre Gönczy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4238951?pdf=render