Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.

Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice.

In most of mammalian embryos, gonadal sex differentiation occurs inside the maternal uterus before birth. In several fetal ovarian grafting experiments using male host mice, an experimental switch from the maternal intrauterine to male-host environment gradually induces partial masculinization of th...

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Main Authors: Kento Miura, Kyoko Harikae, Mayu Nakaguchi, Kenya Imaimatsu, Ryuji Hiramatsu, Ayako Tomita, Yoshikazu Hirate, Masami Kanai-Azuma, Masamichi Kurohmaru, Atsuo Ogura, Yoshiakira Kanai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212367

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https://doi.org/10.1371/journal.pone.0212367

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