Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting

Mapping of Mitochondrial RNA-Protein Interactions by Digital RNase Footprinting

Human mitochondrial DNA is transcribed as long polycistronic transcripts that encompass each strand of the genome and are processed subsequently into mature mRNAs, tRNAs, and rRNAs, necessitating widespread posttranscriptional regulation. Here, we establish methods for massively parallel sequencing...

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Bibliographic Details
Main Authors: Ganqiang Liu, Timothy R. Mercer, Anne-Marie J. Shearwood, Stefan J. Siira, Moira E. Hibbs, John S. Mattick, Oliver Rackham, Aleksandra Filipovska
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005597

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http://www.sciencedirect.com/science/article/pii/S2211124713005597

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