Mutation screening of germline TP53 mutations in high-risk Chinese breast cancer patients

Mutation screening of germline TP53 mutations in high-risk Chinese breast cancer patients

Abstract Background Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is significant. The risk management of TP53 germline mu...

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Bibliographic Details
Main Authors: Ava Kwong, Vivian Yvonne Shin, Cecilia Y. S. Ho, Chun Hang Au, Thomas P. Slavin, Jeffrey N. Weitzel, Tsun-Leung Chan, Edmond S. K. Ma
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Cancer
Subjects:
Hereditary breast cancer
TP53 mutation
Chinese
Breast cancer risk
Online Access:http://link.springer.com/article/10.1186/s12885-020-07476-y

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http://link.springer.com/article/10.1186/s12885-020-07476-y

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