An integrated experimental-computational approach for predicting virulence in New Zealand white rabbits and humans following inhalation exposure to Bacillus anthracis spores.

An integrated experimental-computational approach for predicting virulence in New Zealand white rabbits and humans following inhalation exposure to Bacillus anthracis spores.

Inhalation of Bacillus anthracis spores can lead to an anthrax infection that can be fatal. Previously published mathematical models have extrapolated kinetic rates associated with bacterial growth in New Zealand White (NZW) rabbits to humans, but to date, actual measurements of the underlying proce...

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Bibliographic Details
Main Authors: Becky M Hess, Dennis G Thomas, Thomas J Weber, Janine R Hutchison, Timothy M Straub, Cynthia J Bruckner-Lea, Joshua D Powell, Senthil Kabilan, Richard A Corley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219160

Internet

https://doi.org/10.1371/journal.pone.0219160

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