Silencing of Euchromatic Transposable Elements as a Consequence of Nuclear Lamina Dysfunction

Transposable elements (TEs) are mobile genomic sequences that are normally repressed to avoid proliferation and genome instability. Gene silencing mechanisms repress TEs by RNA degradation or heterochromatin formation. Heterochromatin maintenance is therefore important to keep TEs silent. Loss of he...

Full description

Bibliographic Details
Main Authors: Valeria Cavaliere, Giovanna Lattanzi, Davide Andrenacci
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/3/625