Silencing of Euchromatic Transposable Elements as a Consequence of Nuclear Lamina Dysfunction
Transposable elements (TEs) are mobile genomic sequences that are normally repressed to avoid proliferation and genome instability. Gene silencing mechanisms repress TEs by RNA degradation or heterochromatin formation. Heterochromatin maintenance is therefore important to keep TEs silent. Loss of he...
Main Authors: | Valeria Cavaliere, Giovanna Lattanzi, Davide Andrenacci |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/3/625 |
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