Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress

Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress

Life-threatening ventricular arrhythmias, typically arising from interfaces between fibrosis and surviving cardiomyocytes, are feared sequelae of structurally remodeled hearts under oxidative stress. Incomplete understanding of the proarrhythmic electrical remodeling by fibrosis limits the developme...

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Bibliographic Details
Main Authors: Yali Zhao, Shankar Iyer, Maryam Tavanaei, Nicole T. Nguyen, Andrew Lin, Thao P. Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Physiology
Subjects:
fibrosis
remodeling
oxidative stress
H2O2
cardiomyocyte
myofibroblast
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.622613/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.622613/full

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