Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems

Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems

Reproducibility of microbiome research is a major topic of contemporary interest. Although it is often possible to distinguish individuals with specific diseases within a study, the differences are often inconsistent across cohorts, often due to systematic variation in analytical conditions. Here we...

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Bibliographic Details
Main Authors: Anupriya Tripathi, Zhenjiang Zech Xu, Jin Xue, Orit Poulsen, Antonio Gonzalez, Gregory Humphrey, Michael J. Meehan, Alexey V. Melnik, Gail Ackermann, Dan Zhou, Atul Malhotra, Gabriel G. Haddad, Pieter C. Dorrestein, Rob Knight
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mSystems
Subjects:
cardiovascular
machine learning
metabolism
microbiome
sleep apnea
Online Access:https://doi.org/10.1128/mSystems.00058-19

Internet

https://doi.org/10.1128/mSystems.00058-19

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