Hypoxia and oxidative stress induce sterile placental inflammation in vitro

Abstract Fetal growth restriction (FGR) and stillbirth are associated with placental dysfunction and inflammation and hypoxia, oxidative and nitrative stress are implicated in placental damage. Damage-associated molecular patterns (DAMPs) are elevated in pregnancies at increased risk of FGR and stil...

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Bibliographic Details
Main Authors: Bernadette C. Baker, Alexander E. P. Heazell, Colin Sibley, Rachael Wright, Helen Bischof, Frances Beards, Tatiana Guevara, Sylvie Girard, Rebecca L. Jones
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86268-1