Effects of variation status and enzyme activity for UDP-glucuronosyltransferase 1A1 gene on neonatal hyperbilirubinemia

Background: We found that Taiwanese adults carrying genotypes of UDP-glucuronosyltransferase (UGT) 1A1 with enzyme activity ≤40% of normal were at high risk for developing Gilbert's syndrome. However, the relationship between UGT1A1 activity and neonatal hyperbilirubinemia has never been evalua...

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Bibliographic Details
Main Authors: May-Jen Huang, Yu-Cheng Lin, Kevin Liu, Pi-Feng Chang, Ching-Shan Huang
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957220300887