Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer

Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer

The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers mainly by somatic mutations. This study aimed to assess if polymorphisms of the R...

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Bibliographic Details
Main Authors: Patricio Gonzalez-Hormazabal, Maher Musleh, Marco Bustamante, Juan Stambuk, Raul Pisano, Hector Valladares, Enrique Lanzarini, Hector Chiong, Jorge Rojas, Jose Suazo, V. Gonzalo Castro, Lilian Jara, Zoltan Berger
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Genes
Subjects:
gastric cancer
polymorphism
RAS/RAF/MEK/ERK pathway
MAPK pathway
association study
Online Access:http://www.mdpi.com/2073-4425/10/1/20

Internet

http://www.mdpi.com/2073-4425/10/1/20

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