Design, synthesis and biological evaluation of novel bergapten derivatives as potent lipid lowering agents

The aim of this study was to synthesize novel amide derivatives of bergapten and evaluate their lipid-lowering and triglyceride-lowering activities in mice.  Amide derivatives of bergapten were synthesized by using lactone ring opening strategy in DMSO using NaOH as base followed by alkylation in p...

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Bibliographic Details
Main Authors: Jian-Hong Lu, Zhen Shen, Shu-Xin Zhang, Jin-Yu Zhang
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2015-03-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/21566