A Neutrophil Phenotype Model for Extracorporeal Treatment of Sepsis.

A Neutrophil Phenotype Model for Extracorporeal Treatment of Sepsis.

Neutrophils play a central role in eliminating bacterial pathogens, but may also contribute to end-organ damage in sepsis. Interleukin-8 (IL-8), a key modulator of neutrophil function, signals through neutrophil specific surface receptors CXCR-1 and CXCR-2. In this study a mechanistic computational...

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Bibliographic Details
Main Authors: Alexander D Malkin, Robert P Sheehan, Shibin Mathew, William J Federspiel, Heinz Redl, Gilles Clermont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4607502?pdf=render

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http://europepmc.org/articles/PMC4607502?pdf=render

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