Propofol decreases spike firing frequency with an increase in spike synchronization in the cerebral cortex

Little is known about how propofol modulates the spike firing correlation between excitatory and inhibitory cortical neurons in vivo. We performed extracellular unit recordings from rat insular cortical neurons, and classified neurons with high spontaneous firing frequency, bursting, and short spike...

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Bibliographic Details
Main Authors: Mie Kajiwara, Risako Kato, Yoshiyuki Oi, Masayuki Kobayashi
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319357317