Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions

Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions

Photodynamic therapy (PDT) is used to treat malignancies and precancerous lesions. Near-infrared light delivered by lasers was thought for a while to be the most appropriate option to activate photosensitizers, mostly porphyrins, in the depth of the diseased tissues. More recently, however, several...

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Bibliographic Details
Main Authors: Bastien Doix, Estelle Bastien, Alix Rambaud, Adán Pinto, Caroline Louis, Vincent Grégoire, Olivier Riant, Olivier Feron
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Oncology
Subjects:
photodynamic therapy
photosensitizer
daylight
skin cancer
actinic keratosis
3D model
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00393/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00393/full

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