Evaluating anthracycline cardiotoxicity associated single nucleotide polymorphisms in a paediatric cohort with early onset cardiomyopathy

Evaluating anthracycline cardiotoxicity associated single nucleotide polymorphisms in a paediatric cohort with early onset cardiomyopathy

Abstract Background Anthracyclines are a mainstay of chemotherapy. However, a relatively frequent adverse outcome of anthracycline treatment is cardiomyopathy. Multiple genetic studies have begun to dissect the complex genetics underlying cardiac sensitivity to the anthracycline drug class. A number...

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Bibliographic Details
Main Authors: Timothy N. McOwan, Lauren A. Craig, Anne Tripdayonis, Kathy Karavendzas, Michael M. Cheung, Enzo R. Porrello, Rachel Conyers, David A. Elliott
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cardio-Oncology
Subjects:
Anthracycline induced cardiomyopathy
Genetic variants
Paediatric cancers
Online Access:http://link.springer.com/article/10.1186/s40959-020-00060-0

Internet

http://link.springer.com/article/10.1186/s40959-020-00060-0

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