Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.

Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.

The effect of the cellular reprogramming process per se on mutation load remains unclear. To address this issue, we performed whole exome sequencing analysis of induced pluripotent stem cells (iPSCs) reprogrammed from human cord blood (CB) CD34(+) cells. Cells from a single donor and improved lentiv...

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Bibliographic Details
Main Authors: Rui-Jun Su, Yadong Yang, Amanda Neises, Kimberly J Payne, Jasmin Wang, Kasthuribai Viswanathan, Edward K Wakeland, Xiangdong Fang, Xiao-Bing Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3613421?pdf=render

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http://europepmc.org/articles/PMC3613421?pdf=render

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