Multiparameter telemetry as a sensitive screening method to detect vaccine reactogenicity in mice.

Refined vaccines and adjuvants are urgently needed to advance immunization against global infectious challenges such as HIV, hepatitis C, tuberculosis and malaria. Large-scale screening efforts are ongoing to identify adjuvants with improved efficacy profiles. Reactogenicity often represents a major...

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Bibliographic Details
Main Authors: Margarete Arras, Daniel L Glauser, Paulin Jirkof, Andreas Rettich, Benjamin Schade, Paolo Cinelli, Daniel D Pinschewer, Mathias Ackermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22276127/?tool=EBI