Clonal dissemination, emergence of mutator lineages and antibiotic resistance evolution in Pseudomonas aeruginosa cystic fibrosis chronic lung infection.

Chronic respiratory infection by Pseudomonas aeruginosa is a major cause of mortality in cystic fibrosis (CF). We investigated the interplay between three key microbiological aspects of these infections: the occurrence of transmissible and persistent strains, the emergence of variants with enhanced...

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Bibliographic Details
Main Authors: Carla López-Causapé, Estrella Rojo-Molinero, Xavier Mulet, Gabriel Cabot, Bartolomé Moyà, Joan Figuerola, Bernat Togores, José L Pérez, Antonio Oliver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23951065/?tool=EBI