Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway

Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway

Abstract Background The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified. Herein, this study aims to investigate the role and the underlying mechanism of circ_0003998 in doxorubicin (DOX) resistance in hepatocellular carcinoma (HCC). Methods The expression of...

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Bibliographic Details
Main Authors: Xiaomin Li, Jiefeng He, Xiaojing Ren, Haichao Zhao, Haoliang Zhao
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Diagnostic Pathology
Subjects:
circ_0003998
miR-218-5p
EIF5A2
HCC
Doxorubicin resistance
Online Access:https://doi.org/10.1186/s13000-020-01056-1

Internet

https://doi.org/10.1186/s13000-020-01056-1

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