Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons

Abstract Background RNA localization involves cis-motifs that are recognized by RNA-binding proteins (RBP), which then mediate localization to specific sub-cellular compartments. RNA localization is critical for many different cell functions, e.g., in neuronal dendrites, localization is a critical s...

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Bibliographic Details
Main Authors: Sarah A. Middleton, James Eberwine, Junhyong Kim
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-019-0630-z