Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D.

Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D.

Only a subset of patients will typically respond to any given prescribed drug. The time it takes clinicians to declare a treatment ineffective leaves the patient in an impaired state and at unnecessary risk for adverse drug effects. Thus, diagnostic tests robustly predicting the most effective and s...

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Bibliographic Details
Main Authors: Daniel E Adkins, Renan P Souza, Karolina Aberg, Shaunna L Clark, Joseph L McClay, Patrick F Sullivan, Edwin J C G van den Oord
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566192?pdf=render

Internet

http://europepmc.org/articles/PMC3566192?pdf=render

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