Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein

Custodio et al. characterise a mouse model of ADHD in which thyroid hormone-responsive protein is overexpressed. They demonstrate that reduced levels of striatal triiodothyronine (T3) play a role in inattention and memory impairment in this model and that the model could be used in future studies ex...

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Bibliographic Details
Main Authors: Raly James Perez Custodio, Mikyung Kim, Leandro Val Sayson, Hyun Jun Lee, Darlene Mae Ortiz, Bung-Nyun Kim, Hee Jin Kim, Jae Hoon Cheong
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02633-w