Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice

Electrochemical evidence of nitrate release from the nitrooxy compound 4-((nitrooxy) methyl)-3-nitrobenzoic acid and its antinociceptive and anti-inflammatory activities in mice

Considering the many biological activities of nitric oxide (NO), some lines of research focused on the modulation of these activities through the provision of this mediator by designing and synthesizing compounds coupled with an NO donor group. Thus, the objectives of the present study were to carry...

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Bibliographic Details
Main Authors: Alysson Vinícius Braga, Roger Ryuler Lisboa da Silva, Ianny Bandeira Rodrigues, Gabriel Vitor de Lima Marques, Andre Felippe de Almeida Xavier, Anastacio Boane, Mayara Rodrigues Brandão de Paiva, Pedro Henrique Cavalcanti Franco, Felipe Fernandes Rodrigues, Ivo Souza Ferraz Melo, Armando da Silva Cunha Júnior, Isabela da Costa César, Marília Oliveira Fonseca Goulart, Renata Barbosa de Oliveira, Márcio de Matos Coelho, Renes Resende Machado
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
4-((Nitrooxy) methyl)-3-nitrobenzoic acid
Nitric oxide
Nitrate
Pain
Inflammation
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220311057

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http://www.sciencedirect.com/science/article/pii/S0753332220311057

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