Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α

The current study was undertaken to address the role of mitochondrial reactive oxygen species (ROS), and hypoxia inducible factor-1 alpha (HIF-1α) signaling pathway in the protection against high glucose levels in brain endothelial and NT2 neuron-like cells. Rat brain endothelial cells (RBE4) treate...

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Bibliographic Details
Main Authors: Sónia C. Correia, Renato X. Santos, Sandra M. Cardoso, Maria S. Santos, Catarina R. Oliveira, Paula I. Moreira
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Cyanide
Glucotoxicity
Hypoxia inducible factor-1α
Mitochondria
Mitochondrial network
Preconditioning
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002592

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http://www.sciencedirect.com/science/article/pii/S0969996111002592

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