Surface Functionalization of Orthopedic Titanium Implants with Bone Sialoprotein.

Orthopedic implant failure due to aseptic loosening and mechanical instability remains a major problem in total joint replacement. Improving osseointegration at the bone-implant interface may reduce micromotion and loosening. Bone sialoprotein (BSP) has been shown to enhance bone formation when coat...

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Bibliographic Details
Main Authors: Andreas Baranowski, Anja Klein, Ulrike Ritz, Angelika Ackermann, Joris Anthonissen, Kerstin B Kaufmann, Christian Brendel, Hermann Götz, Pol M Rommens, Alexander Hofmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4844107?pdf=render