Activation of HSD11B1 in the bovine cumulus-oocyte complex during IVM and IVF

The bovine cumulus-oocyte complex (COC) is capable of converting cortisone, an inert glucocorticoid to active cortisol. This mechanism is mediated by 11β-hydroxysteroid oxidoreductase type 1 (HSD11B1), whose expression dramatically increases in the mature COC. In this study, we investigate the time...

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Bibliographic Details
Main Authors: Masafumi Tetsuka, Misato Tanakadate
Format: Article
Language:English
Published: Bioscientifica 2019-07-01
Series:Endocrine Connections
Subjects:
IVM
IVF
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/7/EC-19-0188.xml