Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression

Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression

Nicorandil, a balanced vasodilator, is used in the second-line therapy of angina pectoris. In this study, we aimed to illuminate the effects of nicorandil on inflammation, apoptosis, and atherosclerotic plaque progression. Twenty-five LDL-R -/- mice were fed a high-fat diet for 14 weeks. After 6 wee...

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Bibliographic Details
Main Authors: Max Lenz, Christoph Kaun, Konstantin A. Krychtiuk, Patrick Haider, Mira Brekalo, Nadine Maier, Laura Goederle, Christoph J. Binder, Kurt Huber, Christian Hengstenberg, Johann Wojta, Philipp J. Hohensinner, Walter S. Speidl
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
nicorandil
inflammation
apoptosis
atherosclerosis
plaque
plaque stabilization
Online Access:https://www.mdpi.com/2227-9059/9/2/120

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https://www.mdpi.com/2227-9059/9/2/120

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