Lipocalin-2 Inhibits Osteosarcoma Cell Metastasis by Suppressing MET Expression via the MEK–ERK Pathway

Higher neutrophil-derived cytokine lipocalin-2 (LCN2) expression possesses a versatile role in a myriad of cancers, but little is known about the role of LCN2 on osteosarcoma metastasis. In this study, we demonstrated that higher LCN2 inhibited cellular motility, migration, and invasion of osteosarc...

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Bibliographic Details
Main Authors: Ko-Hsiu Lu, Jia-Sin Yang, Yi-Hsien Hsieh, Hsiao-Ju Chu, Chia-Hsuan Chou, Eric Wun-Hao Lu, Chiao-Wen Lin, Shun-Fa Yang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
MET
Online Access:https://www.mdpi.com/2072-6694/13/13/3181