Evaluation of phosphopeptide enrichment strategies for quantitative TMT analysis of complex network dynamics in cancer-associated cell signalling

Defining alterations in signalling pathways in normal and malignant cells is becoming a major field in proteomics. A number of different approaches have been established to isolate, identify and quantify phosphorylated proteins and peptides. In the current report, a comparison between SCX prefractio...

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Bibliographic Details
Main Authors: Benedetta Lombardi, Nigel Rendell, Mina Edwards, Matilda Katan, Jasminka Godovac Zimmermann
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:EuPA Open Proteomics
Subjects:
TMT
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968515000033