Human Lysozyme Synergistically Enhances Bactericidal Dynamics and Lowers the Resistant Mutant Prevention Concentration for Metronidazole to Helicobacter pylori by Increasing Cell Permeability

Human Lysozyme Synergistically Enhances Bactericidal Dynamics and Lowers the Resistant Mutant Prevention Concentration for Metronidazole to Helicobacter pylori by Increasing Cell Permeability

Metronidazole (MNZ) is an effective agent that has been employed to eradicate Helicobacter pylori (H. pylori). The emergence of broad MNZ resistance in H. pylori has affected the efficacy of this therapeutic agent. The concentration of MNZ, especially the mutant prevention concentration (MPC), plays...

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Bibliographic Details
Main Authors: Xiaolin Zhang, Anmin Jiang, Hao Yu, Youyi Xiong, Guoliang Zhou, Meisong Qin, Jinfeng Dou, Jianfei Wang
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
H. pylori
metronidazole
human lysozyme
mutant prevention concentration
bactericidal dynamics
Online Access:http://www.mdpi.com/1420-3049/21/11/1435

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http://www.mdpi.com/1420-3049/21/11/1435

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