LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer

<p>Abstract</p> <p>Background</p> <p>Most colorectal carcinomas are driven by an activation of the canonical Wnt signalling pathway, which promotes the expression of multiple target genes mediating proliferation inavasion and invasion. Upon activation of the Wnt signall...

Full description

Bibliographic Details
Main Authors: Kirchner Thomas, Engel Jutta, Reiche Jana A, Horst David, Kriegl Lydia, Jung Andreas
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/123