Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium

Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium

Nitric oxide (NO·) produced by mammalian cells exerts antimicrobial actions that result primarily from the modification of protein thiols (S-nitrosylation) and metal centers. A comprehensive approach was used to identify novel targets of NO· in Salmonella enterica serovar Typhimurium (S. Typhimurium...

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Bibliographic Details
Main Authors: Elaine R. Frawley, Joyce E. Karlinsey, Anshika Singhal, Stephen J. Libby, Paschalis-Thomas Doulias, Harry Ischiropoulos, Ferric C. Fang
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mBio
Subjects:
Salmonella
nitric oxide
pathogenesis
transporters
zinc homeostasis
Online Access:https://doi.org/10.1128/mBio.01040-18

Internet

https://doi.org/10.1128/mBio.01040-18

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