Critical Issues in BDNF Val66Met Genetic Studies of Neuropsychiatric Disorders
Neurotrophins have been implicated in the pathophysiology of many neuropsychiatric diseases. Brain-derived neurotrophic factor (BDNF) is the most abundant and widely distributed neurotrophin in the brain. Its Val66Met polymorphism (refSNP Cluster Report: rs6265) is a common and functional single-nuc...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2018-05-01
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Series: | Frontiers in Molecular Neuroscience |
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Online Access: | http://journal.frontiersin.org/article/10.3389/fnmol.2018.00156/full |