Infection in a rat model reactivates attenuated virulence after long-term axenic culture of Acanthamoeba spp

Prolonged culturing of many microorganisms leads to the loss of virulence and a reduction of their infective capacity. However, little is known about the changes in the pathogenic strains of Acanthamoeba after long culture periods. Our study evaluated the effect of prolonged culturing on the invasiv...

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Bibliographic Details
Main Authors: Carolina De Marco Verissimo, Vinicius Jose Maschio, Ana Paula Folmer Correa, Adriano Brandelli, Marilise Brittes Rott
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2013-11-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000700832&lng=en&tlng=en