Quercetin protects human brain microvascular endothelial cells from fibrillar β-amyloid1–40-induced toxicity

Amyloid beta-peptides (Aβ) are known to undergo active transport across the blood-brain barrier, and cerebral amyloid angiopathy has been shown to be a prominent feature in the majority of Alzheimer׳s disease. Quercetin is a natural flavonoid molecule and has been demonstrated to have potent neuropr...

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Bibliographic Details
Main Authors: Yongjie Li, Sibai Zhou, Jinze Li, Yuhua Sun, Hamlati Hasimu, Rui Liu, Tiantai Zhang
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383514001245