Three isoforms of exosomal circPTGR1 promote hepatocellular carcinoma metastasis via the miR449a–MET pathwayResearch in context

Background: The role of exosomal circular RNAs (circRNAs) in Hepatocellular carcinoma (HCC) cells with high metastatic potential has been little studied. Methods: Exosomal circRNA from cells with non-metastatic (HepG2), low metastatic (97L), and high metastatic (LM3) potential were sequencing. Metas...

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Bibliographic Details
Main Authors: Guoying Wang, Wei Liu, Yong Zou, Genshu Wang, Yinan Deng, Jingyan Luo, Yingcai Zhang, Hua Li, Qi Zhang, Yang Yang, Guihua Chen
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830639X