Sp100 colocalizes with HPV replication foci and restricts the productive stage of the infectious cycle.

We have shown previously that Sp100 (a component of the ND10 nuclear body) represses transcription, replication and establishment of incoming human papillomavirus (HPV) DNA in the early stages of infection. In this follow up study, we show that Sp100 does not substantially regulate viral infection i...

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Bibliographic Details
Main Authors: Wesley H Stepp, James D Stamos, Simran Khurana, Alix Warburton, Alison A McBride
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5638619?pdf=render