Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects.

Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects.

BACKGROUND: Spermatogenesis is a complex biological process that requires a highly specialized control of gene expression. In the past decade, small non-coding RNAs have emerged as critical regulators of gene expression both at the transcriptional and post-transcriptional level. DICER1, an RNAse III...

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Main Authors: Yannick Romero, Oliver Meikar, Marilena D Papaioannou, Béatrice Conne, Corinne Grey, Manuela Weier, François Pralong, Bernard De Massy, Henrik Kaessmann, Jean-Dominique Vassalli, Noora Kotaja, Serge Nef
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3187767?pdf=render

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