Alteration of NMDA receptor trafficking as a cellular hallmark of psychosis

Abstract A dysfunction of the glutamatergic transmission, especially of the NMDA receptor (NMDAR), constitutes one of the main biological substrate of psychotic disorders, such as schizophrenia. The NMDAR signaling hypofunction, through genetic and/or environmental insults, would cause a neurodevelo...

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Bibliographic Details
Main Authors: Agnès Espana, Henrik Seth, Julie Jézéquel, Tingting Huang, Delphine Bouchet, Marylin Lepleux, Hélène Gréa, Karl Bechter, Marion Schneider, Eric Hanse, Laurent Groc
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01549-7