Alteration of NMDA receptor trafficking as a cellular hallmark of psychosis
Abstract A dysfunction of the glutamatergic transmission, especially of the NMDA receptor (NMDAR), constitutes one of the main biological substrate of psychotic disorders, such as schizophrenia. The NMDAR signaling hypofunction, through genetic and/or environmental insults, would cause a neurodevelo...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-021-01549-7 |